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ERIC Number: EJ937828
Record Type: Journal
Publication Date: 2009
Pages: 4
Abstractor: As Provided
Reference Count: 13
ISSN: ISSN-0021-9266
What Can a Micronucleus Teach? Learning about Environmental Mutagenesis
Linde, Ana R.; Garcia-Vazquez, Eva
Journal of Biological Education, v43 n2 p85-88 2009
The micronucleus test is widely employed in environmental health research. It can also be an excellent tool for learning important concepts in environmental health. In this article we present an inquiry-based laboratory exercise where students explore several theoretical and practical aspects of environmental mutagenesis employing the micronucleus as a central landmark. Performing the test in mussels exposed to colchicine and comparing the results with a control group, they learn (or refresh previous concepts) about cytogenetics and chromosome segregation in cell divisions; about DNA molecular structure and how it can be altered by different agents (mutagenesis); and about the value of basic genetic processes for applied research, for example biomarkers. (Contains 1 figure and 1 table.)
Routledge. Available from: Taylor & Francis, Ltd. 325 Chestnut Street Suite 800, Philadelphia, PA 19106. Tel: 800-354-1420; Fax: 215-625-2940; Web site:
Publication Type: Journal Articles; Reports - Evaluative
Education Level: N/A
Audience: N/A
Language: English
Sponsor: N/A
Authoring Institution: N/A