ERIC Number: EJ936810
Record Type: Journal
Publication Date: 2011
Abstractor: As Provided
Reference Count: 0
Neural Bases of Recovery after Brain Injury
Nudo, Randolph J.
Journal of Communication Disorders, v44 n5 p515-520 Sep-Oct 2011
Substantial data have accumulated over the past decade indicating that the adult brain is capable of substantial structural and functional reorganization after stroke. While some limited recovery is known to occur spontaneously, especially within the first month post-stroke, there is currently significant optimism that new interventions based on the modulation of neuroplasticity mechanisms will provide greater functional benefits in a larger population of stroke survivors. To place this information in the context of current thinking about brain plasticity, this review outlines the basic theories of why spontaneous recovery occurs, and introduces important principles to explain the effects of post-stroke behavioral experience on neural plasticity. Learning outcomes: Readers will be able to: (a) explain the three classic theories to explain spontaneous recovery after focal brain injury, (b) explain the neurophysiological effects of post-injury rehabilitative therapy on functional organization in motor cortex, (c) readers will be able to describe some of the variables that impact the effects of post-stroke behavioral experience on neuroplasticity, and (d) readers will be able to explain some of the current laboratory-based approaches to modifying brain circuits after stroke that might soon be translated to human application.
Descriptors: Neurological Impairments, Injuries, Brain, Intervention, Neurology, Physiology, Rehabilitation, Therapy, Brain Hemisphere Functions, Scientific Research
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Publication Type: Journal Articles; Reports - Evaluative
Education Level: N/A
Authoring Institution: N/A