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ERIC Number: EJ915732
Record Type: Journal
Publication Date: 2011
Pages: 8
Abstractor: As Provided
Reference Count: 0
ISSN: ISSN-0891-4222
Cardiac Autonomic Function during Submaximal Treadmill Exercise in Adults with Down Syndrome
Mendonca, Goncalo V.; Pereira, Fernando D.; Fernhall, Bo
Research in Developmental Disabilities: A Multidisciplinary Journal, v32 n2 p532-539 Mar-Apr 2011
This study determined whether the cardiac autonomic function of adults with Down syndrome (DS) differs from that of nondisabled persons during submaximal dynamic exercise. Thirteen participants with DS and 12 nondisabled individuals performed maximal and submaximal treadmill tests with metabolic and heart rate (HR) measurements. Spectral analysis of HR variability was performed on the last 256 consecutive R-R intervals obtained under the following conditions: (1) rest, (2) submaximal treadmill exercise (at constant relative intensity below the ventilatory threshold) and (3) recovery. Participants with DS presented lower chronotropic response than those without DS to peak and submaximal exercise (p less than 0.05). Nevertheless, the fractional utilization of peak HR during treadmill walking was similar between groups (approximately 60% peak HR). Even though there were no between-group differences at rest or during recovery, the participants with DS showed a higher LF/HF ratio during exercise (p less than 0.05). Similarly, the LF power of participants with DS during exercise was greater than that of nondisabled participants (p less than 0.05). In contrast, both groups exhibited similar HF power at each physiological condition. In conclusion, these findings suggest that adults with DS demonstrate appropriate vagal withdrawal, but heightened sympathetic modulation of HR variability at approximately 60% of their peak HR. Despite this, the absolute change in HR from rest to exercise was attenuated in these individuals compared to persons without disabilities. This indicates that DS may be associated with poor cardiac responsiveness to changes in autonomic modulation during exercise at intensities below the ventilatory threshold. (Contains 2 figures and 1 table.)
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Publication Type: Journal Articles; Reports - Research
Education Level: N/A
Audience: N/A
Language: English
Sponsor: N/A
Authoring Institution: N/A