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ERIC Number: EJ912250
Record Type: Journal
Publication Date: 2011-Feb
Pages: 10
Abstractor: As Provided
Reference Count: 31
ISSN: ISSN-0162-3257
Evaluation of a Records-Review Surveillance System Used to Determine the Prevalence of Autism Spectrum Disorders
Avchen, Rachel Nonkin; Wiggins, Lisa D.; Devine, Owen; Van Naarden Braun, Kim; Rice, Catherine; Hobson, Nancy C.; Schendel, Diana; Yeargin-Allsopp, Marshalyn
Journal of Autism and Developmental Disorders, v41 n2 p227-236 Feb 2011
We conducted the first study that estimates the sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of a population-based autism spectrum disorders (ASD) surveillance system developed at the Centers for Disease Control and Prevention. The system employs a records-review methodology that yields ASD classification (case versus non-ASD case) and was compared with classification based on clinical examination. The study enrolled 177 children. Estimated specificity (0.96, [CI 0.95 = 0.94, 0.99]), PPV (0.79 [CI 0.95 = 0.66, 0.93]), and NPV (0.91 [CI 0.95 = 0.87, 0.96]) were high. Sensitivity was lower (0.60 [CI .95 = 0.45, 0.75]). Given diagnostic heterogeneity, and the broad array of ASD in the population, identifying children with ASD is challenging. Records-based surveillance yields a population-based estimate of ASD that is likely conservative.
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Publication Type: Journal Articles; Reports - Research
Education Level: N/A
Audience: N/A
Language: English
Sponsor: N/A
Authoring Institution: N/A