ERIC Number: EJ909015
Record Type: Journal
Publication Date: 2010-Nov
Abstractor: As Provided
Reference Count: 0
Seizures in Fragile X Syndrome: Characteristics and Comorbid Diagnoses
Berry-Kravis, Elizabeth; Raspa, Melissa; Loggin-Hester, Lisa; Bishop, Ellen; Holiday, David; Bailey, Donald B., Jr.
American Journal on Intellectual and Developmental Disabilities, v115 n6 p461-472 Nov 2010
A national survey of caregivers of individuals with fragile X syndrome addressed characteristics of epilepsy and co-occurring conditions. Of the 1,394 individuals (1,090 males and 304 females) with the full mutation, 14% of males and 6% of females reported seizures. Seizures were more often partial, began between ages 4 and 10 years, and were infrequent and easily treated. Similar characteristics and patterns were seen in medical chart review data from a large clinic cohort of patients with fragile X syndrome. National survey data showed that autism was significantly associated with seizures as a co-occurring condition. Although seizures in fragile X syndrome are typically not severe and easily treated with medications, they appear to be associated with developmental-behavioral comorbidity that impacts function.
Descriptors: Seizures, Caregivers, National Surveys, Disabilities, Genetic Disorders, Symptoms (Individual Disorders), Age Differences, Autism, Epilepsy, Gender Differences, Developmental Delays
American Association on Intellectual and Developmental Disabilities. P.O. Box 1897, Lawrence, KS 66044-1897. Tel: 785-843-1235; Fax: 785-843-1274; e-mail: AJMR@allenpress.com; Web site: http://aaidd.allenpress.com
Publication Type: Journal Articles; Reports - Evaluative
Education Level: N/A
Authoring Institution: N/A