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ERIC Number: EJ904480
Record Type: Journal
Publication Date: 2005-Dec
Pages: 8
Abstractor: As Provided
Reference Count: 61
ISSN: ISSN-1080-4013
Applications of Gene Targeting Technology to Mental Retardation and Developmental Disability Research
Pimenta, Aurea F.; Levitt, Pat
Mental Retardation and Developmental Disabilities Research Reviews, v11 n4 p295-302 Dec 2005
The human and mouse genome projects elucidated the sequence and position map of innumerous genes expressed in the central nervous system (CNS), advancing our ability to manipulate these sequences and create models to investigate regulation of gene expression and function. In this article, we reviewed gene targeting methodologies with emphasis on applications to CNS development and neurodevelopmental disorders. (Contains 4 figures.)
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Publication Type: Journal Articles; Reports - Evaluative
Education Level: N/A
Audience: N/A
Language: English
Sponsor: N/A
Authoring Institution: N/A