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ERIC Number: EJ903066
Record Type: Journal
Publication Date: 2010-Nov
Pages: 11
Abstractor: As Provided
Reference Count: 73
ISBN: N/A
ISSN: ISSN-1087-0547
Corpus Callosum Anatomy in Chronically Treated and Stimulant Naive ADHD
Schnoebelen, Sarah; Semrud-Clikeman, Margaret; Pliszka, Steven R.
Journal of Attention Disorders, v14 n3 p256-266 Nov 2010
Objective: To determine the effect of chronic stimulant treatment on corpus callosum (CC) size in children with ADHD using volumetric and area measurements. Previously published research indicated possible medication effects on specific areas of the CC. Method: Measurements of the CC from anatomical MRIs were obtained from children aged 9-16 in three diagnostic groups (a) chronically treated ADHD, (b) stimulant-naive ADHD, and (c) typically developing children. Results: The three groups did not differ in overall CC volume. Additional analyses found differences in the area of the splenium, with the treatment-naive group exhibiting the smallest area. Conclusions: Previously reported reductions of CC size in ADHD samples do not appear to be a result of chronic stimulant treatment. The current study suggested a trend toward normalization of splenium size for participants treated with stimulant medication. (Contains 2 tables.)
SAGE Publications. 2455 Teller Road, Thousand Oaks, CA 91320. Tel: 800-818-7243; Tel: 805-499-9774; Fax: 800-583-2665; e-mail: journals@sagepub.com; Web site: http://sagepub.com
Publication Type: Journal Articles; Reports - Research
Education Level: N/A
Audience: N/A
Language: English
Sponsor: N/A
Authoring Institution: N/A
Identifiers - Assessments and Surveys: Diagnostic Interview Schedule for Children