ERIC Number: EJ899607
Record Type: Journal
Publication Date: 2010
Reference Count: 12
Proteopedia: A Collaborative, Virtual 3D Web-Resource for Protein and Biomolecule Structure and Function
Hodis, Eran; Prilusky, Jaime, Sussman, Joel L.
Biochemistry and Molecular Biology Education, v38 n5 p341-342 Sep-Oct 2010
Protein structures are hard to represent on paper. They are large, complex, and three-dimensional (3D)--four-dimensional if conformational changes count! Unlike most of their substrates, which can easily be drawn out in full chemical formula, drawing every atom in a protein would usually be a mess. Simplifications like showing only the surface of the protein or showing only a trace between its alpha carbons are preferred methods for representing the overall structure of a protein, and zoomed-in views showing all of the atoms in a certain part of the protein can highlight important residues. Unfortunately, even these simplifications can look confusing when flattened into two-dimensional images as in printed textbooks and scientific publications. This article introduces "Proteopedia" (http:/www.proteopedia.org), a new collaborative web resource with pages describing protein, nucleic acid, and other biomolecule structures--including complexes--in interactive, virtual 3D. Educators have found "Proteopedia" to be a useful teaching tool, and several instructors have adopted "Proteopedia" into their classrooms. The most obvious use is viewing existing user-added pages on molecules of interest.
Descriptors: Genetics, Educational Technology, Molecular Biology, Web Sites, Technology Uses in Education, Technology Integration, Computer Software Reviews, Cytology, Educational Resources, Molecular Structure
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Publication Type: Journal Articles; Reports - Descriptive
Education Level: Higher Education
Authoring Institution: N/A