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ERIC Number: EJ897282
Record Type: Journal
Publication Date: 2010-Sep
Pages: 13
Abstractor: As Provided
Reference Count: 57
ISBN: N/A
ISSN: ISSN-1082-989X
Testing Multiple Outcomes in Repeated Measures Designs
Lix, Lisa M.; Sajobi, Tolulope
Psychological Methods, v15 n3 p268-280 Sep 2010
This study investigates procedures for controlling the familywise error rate (FWR) when testing hypotheses about multiple, correlated outcome variables in repeated measures (RM) designs. A content analysis of RM research articles published in 4 psychology journals revealed that 3 quarters of studies tested hypotheses about 2 or more outcome variables. Several procedures originally proposed for testing multiple outcomes in 2-group designs are extended to 2-group RM designs. The investigated procedures include 2 modified Bonferroni procedures that adjust the level of significance, alpha, for the effective number of outcomes and a permutation step-down (PSD) procedure. The FWR, any-variable power, and all-variable power are investigated in a Monte Carlo study. One modified Bonferroni procedure frequently resulted in inflated FWRs, whereas the PSD procedure controlled the FWR. The PSD procedure could be substantially more powerful than the conventional Bonferroni procedure, which does not account for dependencies among the outcome variables. However, the difference in power between the PSD procedure, which does account for these dependencies, and Hochberg's step-up procedure, which does not, were negligible. A numeric example illustrates implementation of these multiple-testing procedures. (Contains 6 tables.)
American Psychological Association. Journals Department, 750 First Street NE, Washington, DC 20002-4242. Tel: 800-374-2721; Tel: 202-336-5510; Fax: 202-336-5502; e-mail: order@apa.org; Web site: http://www.apa.org/publications
Publication Type: Journal Articles; Reports - Research
Education Level: N/A
Audience: N/A
Language: English
Sponsor: N/A
Authoring Institution: N/A