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ERIC Number: EJ889709
Record Type: Journal
Publication Date: 2010-May
Pages: 8
Abstractor: As Provided
Reference Count: 10
ISSN: ISSN-1539-2422
Analyzing Population Genetics Using the Mitochondrial Control Region and Bioinformatics
Sato, Takumi; Phillips, Bonnie; Latourelle, Sandra M.; Elwess, Nancy L.
Bioscene: Journal of College Biology Teaching, v36 n1 p26-33 May 2010
The 14-base pair hypervariable region in mitochondrial DNA (mtDNA) of Asian populations, specifically Japanese and Chinese students at Plattsburgh State University, was examined. Previous research on this 14-base pair region showed it to be susceptible to mutations and as a result indicated direct correlation with specific ethnic populations. Earlier studies provided the 14-base pair region sequence analysis for Asians in general. This inquiry-based project was generated in a junior/senior college general genetics course. The project produced sequences of the 14-base pair hypervariable region for Japanese and Chinese populations, specifically. The investigation examined 28 Japanese and 27 Chinese international students. A Control group, consisting of 20 random students was also sampled. The 14-base pair hypervariable region for each sample was analyzed through comparison using bioinformatics. Analyzing the samples showed that, overall, 46% of the Japanese samples, 59% of the Chinese samples, and 75% of the Control samples had the same 14-base pair sequence. In addition to this, it was observed that the Japanese, Chinese, and Control group all had their own specific mutations within the 14-base pair hypervariable region. (Contains 3 figures and 2 tables.)
Association of College and Biology Educators. Web site:
Publication Type: Journal Articles; Reports - Research
Education Level: Higher Education; Postsecondary Education
Audience: N/A
Language: English
Sponsor: N/A
Authoring Institution: N/A
Identifiers - Location: New York