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ERIC Number: EJ885670
Record Type: Journal
Publication Date: 2010-Jun
Pages: 7
Abstractor: As Provided
Reference Count: 28
ISSN: ISSN-0012-1622
Reading Performance Correlates with White-Matter Properties in Preterm and Term Children
Andrews, James S.; Ben-Shachar, Michal; Yeatman, Jason D.; Flom, Lynda L.; Luna, Beatriz; Feldman, Heidi M.
Developmental Medicine & Child Neurology, v52 n6 pe94-e100 Jun 2010
Aim: We used diffusion tensor imaging to investigate the association between white-matter integrity and reading ability in a cohort of 28 children. Nineteen preterm children (14 males, five females; mean age 11y 11mo [SD 1y 10mo], mean gestational age 30.5wks (SD 3.2), mean birthweight was 1455g [SD 625]); and nine term children (five males, four females; mean age 12y 8mo [SD 2y 5mo], mean gestational age 39.6wks (SD 1.2), and mean birthweight 3877g [SD 473]). Method: We tested whether fractional anisotropy in a left hemisphere temporoparietal region and in the corpus callosum correlates with birthweight and scores on the following three subtests of the Woodcock-Johnson III Tests of Achievement: word identification, word attack, and passage comprehension. Results: Preterm children had lower reading scores than a comparison group for all reading subtests (p less than 0.05). We found significant correlations between birthweight and fractional anisotropy in the whole corpus callosum (p = 0.001), and between fractional anisotropy and reading skill in the genu (p = 0.001) and body (p = 0.001) of the corpus callosum. The correlation between reading skill and fractional anisotropy in a left temporoparietal region previously associated with reading disability was not significant (p = 0.095). Interpretation: We conclude that perinatal white-matter injury of the central corpus callosum may have long-term developmental implications for reading performance. (Contains 2 tables and 3 figures.)
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Publication Type: Journal Articles; Reports - Research
Education Level: N/A
Audience: N/A
Language: English
Sponsor: N/A
Authoring Institution: N/A
Identifiers - Assessments and Surveys: Woodcock Johnson Tests of Achievement