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ERIC Number: EJ878960
Record Type: Journal
Publication Date: 2010-Mar
Pages: 4
Abstractor: As Provided
Reference Count: N/A
ISSN: ISSN-0012-1622
Sibling Sex Ratio of Individuals Diagnosed with Autism Spectrum Disorder as Children
Mouridsen, Svend Erik; Rich, Bente; Isager, Torben
Developmental Medicine & Child Neurology, v52 n3 p289-292 Mar 2010
Aim: To study the sex ratio (proportion of males) in siblings of individuals diagnosed with autism spectrum disorders (ASDs) as children. Method: In the current study, we extended previous studies dealing with the androgen theory of autism and examined sex ratios in the siblings of 326 individuals with ASD (245 males, 81 females) who had been consecutively assessed at two Danish university clinics of child psychiatry during the 25-year period from 1960 to 1985. Results: Among the 513 siblings, 300 were males and 213 females. This yields a sex ratio of 0.585, which is significantly higher than the Danish live-birth sex ratio over the same period (0.514, p=0.001). The sibling sex ratio was not associated with the IQ in the autistic probands. Interpretation: Our findings suggest a potential indirect confirmation of the androgen theory of autism.
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Publication Type: Journal Articles; Reports - Evaluative
Education Level: N/A
Audience: N/A
Language: English
Sponsor: N/A
Authoring Institution: N/A
Identifiers - Location: Denmark