ERIC Number: EJ878610
Record Type: Journal
Publication Date: 2010-Apr
Abstractor: As Provided
Reference Count: 0
D-Cycloserine Augmentation of Cognitive-Behavioral Therapy: Directions for Pilot Research in Pediatric Obsessive-Compulsive Disorder
Storch, Eric A.; McKay, Dean; Reid, Jeannette M.; Geller, Daniel A.; Goodman, Wayne K.; Lewin, Adam B.; Murphy, Tanya K.
Child & Youth Care Forum, v39 n2 p101-112 Apr 2010
This paper discusses a recent translational success in combining behavioral psychotherapy with a novel medication, d-cycloserine (DCS), to augment cognitive-behavioral therapy (CBT) for anxiety disorders. The literature on behavioral theory of exposure-based therapies is provided, followed by a discussion of the role of DCS in enhancing extinction learning that is core to such therapies. As well, pragmatic issues such as dosing and timing are discussed. The manuscript is concluded with consideration of future directions in DCS augmentation in the form of a pilot trial investigating DCS augmentation of CBT in pediatric patients with obsessive-compulsive disorder.
Descriptors: Cognitive Restructuring, Patients, Psychotherapy, Anxiety Disorders, Behavior Modification, Drug Therapy, Role, Futures (of Society), Pediatrics, Outcomes of Treatment
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Publication Type: Journal Articles; Reports - Descriptive
Education Level: N/A
Authoring Institution: N/A