ERIC Number: EJ858669
Record Type: Journal
Publication Date: 2009-Nov
Abstractor: As Provided
Auditory Brainstem Evoked Responses in Newborns with Down Syndrome
Kittler, Phyllis M.; Phan, Ha T. T.; Gardner, Judith M.; Miroshnichenko, Inna; Gordon, Anne; Karmel, Bernard Z.
American Journal on Intellectual and Developmental Disabilities, v114 n6 p393-400 Nov 2009
Auditory brainstem evoked responses (ABRs) were compared in 15 newborns with Down syndrome and 15 sex-, age-, and weight-matched control newborns. Participants had normal ABRs based upon values specific to 32- to 42-weeks postconceptional age. Although Wave III and Wave V component latencies and the Wave I-III interpeak latency (IPL) were shorter in ABRs of infants with Down syndrome, the Wave III-V IPL was not, pointing to anomalies in the lower rather than upper brainstem auditory pathways. Shorter Down syndrome ABR latencies have been reported at many ages. Extending these findings to newborns suggests that the underlying basis for this develops prenatally. ABR patterns in infants with Down syndrome were similar to reports for intrauterine growth restricted newborns.
Descriptors: Down Syndrome, Neonates, Control Groups, Brain, Cognitive Development, Auditory Stimuli, Comparative Analysis, Prenatal Influences, Child Development
American Association on Intellectual and Developmental Disabilities. P.O. Box 1897, Lawrence, KS 66044-1897. Tel: 785-843-1235; Fax: 785-843-1274; e-mail: AJMR@allenpress.com; Web site: http://aaidd.allenpress.com
Publication Type: Journal Articles; Reports - Research
Education Level: Early Childhood Education
Authoring Institution: N/A