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ERIC Number: EJ853655
Record Type: Journal
Publication Date: 2003
Pages: 4
Abstractor: ERIC
ISSN: ISSN-1536-7509
Video Views and Reviews
Watters, Christopher
Cell Biology Education, v2 n3 p137-140 Fall 2003
Neutrophils are white blood cells specialized for scavenging cellular debris and consuming infectious microorganisms in a process called "phagocytosis." What seems to make neutrophils especially voracious is the presence of antibodies (or opsonins) coating the surface of foreign cells. Recently, Dewitt and Hallett (2002) examined the role of cytoplasmic calcium in mediating neutrophil phagocytosis of opsonin-coated particles, using neutrophils that had been loaded with a compound (Fura-2) that changes its fluorescence properties when it binds with calcium. Their observations are accompanied by two videos, the first recording changes in calcium concentrations as an opsonized particle is phagocytosed, and the second exhibiting similar changes when a particle is touched to the surface of a neutrofil and then withdrawn. In this article, the author reviews these videos. (Contains 4 figures.)
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Publication Type: Journal Articles; Reports - Evaluative
Education Level: N/A
Audience: N/A
Language: English
Sponsor: N/A
Authoring Institution: N/A