The purpose of this study was to examine the direct and indirect effects of science process skills, logical thinking abilities, attitudes towards science, and locus of control on science achievement among Form 4 students in the Interior Division of Sabah, Malaysia. Research findings showed that there were low to moderate, positive but significant correlation among science process skills, logical thinking abilities, attitudes towards science, locus of control, and science achievement for all respondents. The research findings bring some meaningful implications to those who are involved directly or indirectly in the research and development of science education and training of science teachers especially in the Interior Division of Sabah, Malaysia. (Contains 4 tables and 1 figure.)