ERIC Number: EJ843529
Record Type: Journal
Publication Date: 2009-Jul
Abstractor: As Provided
Reference Count: 27
The Treatment of Challenging Behaviour in Intellectual Disabilities: Cost-Effectiveness Analysis
Romeo, R.; Knapp, M.; Tyrer, P.; Crawford, M.; Oliver-Africano, P.
Journal of Intellectual Disability Research, v53 n7 p633-643 Jul 2009
Background: Antipsychotic drugs are used in the routine treatment of adults with intellectual disabilities (ID) and challenging behaviour in the UK despite limited evidence of their effectiveness. There is no evidence on their cost-effectiveness. Methods: The relative cost-effectiveness of risperidone, haloperidol and placebo in treating individuals with an ID and challenging behaviour was compared from a societal perspective in a 26-week, double-blind, randomised controlled trial. Outcomes were changes in aggression and quality of life. Costs measured all service impacts and unpaid caregiver inputs. Results: After 26 weeks, patients randomised to placebo had lower costs compared with those in the risperidone and haloperidol treatment groups. Aggression was highest for patients treated with risperidone and lowest for patients treated with haloperidol; however, quality of life was lowest for patients treated with haloperidol and highest for patients treated with risperidone. Conclusion: The treatment of challenging behaviour in ID with antipsychotic drugs is not a cost-effective option.
Descriptors: Mental Retardation, Quality of Life, Outcomes of Treatment, Cost Effectiveness, Behavior Problems, Behavior Modification, Foreign Countries, Adults, Drug Therapy, Aggression, Costs
Blackwell Publishing. 350 Main Street, Malden, MA 02148. Tel: 800-835-6770; Tel: 781-388-8599; Fax: 781-388-8232; e-mail: email@example.com; Web site: http://www.blackwellpublishing.com/jnl_default.asp
Publication Type: Journal Articles; Reports - Evaluative
Education Level: N/A
Authoring Institution: N/A
Identifiers - Location: United Kingdom