NotesFAQContact Us
Search Tips
Peer reviewed Peer reviewed
Direct linkDirect link
ERIC Number: EJ838103
Record Type: Journal
Publication Date: 2009-Apr
Pages: 4
Abstractor: As Provided
Reference Count: 24
ISSN: ISSN-1072-0502
The Hippocampus Supports Encoding of Between-Domain Associations within Working Memory
Piekema, Carinne; Kessel, Roy P. C.; Rijpkema, Mark; Fernandez, Guillen
Learning & Memory, v16 n4 p231-234 Apr 2009
It has been established that the medial temporal lobe, including the hippocampus, is crucial for associative memory. The aim of the current functional magnetic resonance imaging (fMRI) study was to investigate whether the hippocampus is differentially activated for associations between items processed in the same neocortical region (within-domain) as compared with associations between items processed in different neocortical regions (between-domain). Here, we show that the hippocampus is significantly more active for between-domain associations compared with within-domain associations. Thus, the hippocampus is important for associative encoding, and furthermore, shows greater activation when the stimuli to be associated come from different stimulus categories. (Contains 2 tables and 2 figures.)
Cold Spring Harbor Laboratory Press. 500 Sunnyside Boulevard, Woodbury, NY 11797-2924. Tel: 800-843-4388; Tel: 516-367-8800; Fax: 516-422-4097; e-mail:; Web site:
Publication Type: Journal Articles; Reports - Research
Education Level: N/A
Audience: N/A
Language: English
Sponsor: N/A
Authoring Institution: N/A