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ERIC Number: EJ837499
Record Type: Journal
Publication Date: 2009-Jul
Pages: 9
Abstractor: As Provided
Reference Count: 0
ISSN: ISSN-0278-2626
Temporal Sequence of Hemispheric Network Activation during Semantic Processing: A Functional Network Connectivity Analysis
Assaf, Michal; Jagannathan, Kanchana; Calhoun, Vince; Kraut, Michael; Hart, John, Jr.; Pearlson, Godfrey
Brain and Cognition, v70 n2 p238-246 Jul 2009
To explore the temporal sequence of, and the relationship between, the left and right hemispheres (LH and RH) during semantic memory (SM) processing we identified the neural networks involved in the performance of functional MRI semantic object retrieval task (SORT) using group independent component analysis (ICA) in 47 healthy individuals. SORT requires participants to determine whether word pairs describing object features combine to retrieve an object. Functional network connectivity (FNC) was used to assess the correlations between components' time courses. Results showed that semantic left and right hemisphere networks comprise two independent ICA components. The components' time courses were highly correlated and RH activation preceded that of the LH. Moreover, this correlation was significantly stronger in better vs. poorer performers of the SORT. These results indicate an early activation of the RH that is closely followed by activation of the LH, to facilitate performance during word retrieval from SM. (Contains 2 tables and 2 figures.)
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Publication Type: Journal Articles; Reports - Research
Education Level: N/A
Audience: N/A
Language: English
Sponsor: N/A
Authoring Institution: N/A