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ERIC Number: EJ835783
Record Type: Journal
Publication Date: 2007-Dec
Pages: 6
Abstractor: As Provided
Reference Count: 6
ISBN: N/A
ISSN: ISSN-1479-7860
Dice and DNA
Wernersson, Rasmus
Bioscience Education e-Journal, v10 Article 5 Dec 2007
An important part of teaching students how to use the BLAST tool for searching large sequence databases, is to train the students to think critically about the quality of the sequence hits found--both in terms of the statistical significance and how informative the individual hits are. This paper describes how generating truly random sequences by throwing dice can be used to illustrate how unrelated sequences may be found by BLAST, how to judge the statistical significance of the hits, and how the database size influences the statistics. (Contains 3 figures, 1 table and 1 footnote.)
Centre for Bioscience, The Higher Education Academy. Room 9.15, Worsley Building, University of Leeds, Leeds LS2 9JT United Kingdom. Tel: +44-113-343-3001; Fax: +44-113-343-5894; e-mail: beej@leeds.ac.uk; Website: http://www.bioscience.heacademy.ac.uk/journal
Publication Type: Journal Articles; Reports - Descriptive
Education Level: N/A
Audience: N/A
Language: English
Sponsor: N/A
Authoring Institution: N/A