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ERIC Number: EJ830324
Record Type: Journal
Publication Date: 2009
Pages: 7
Abstractor: As Provided
Reference Count: 50
ISBN: N/A
ISSN: ISSN-0160-2896
Imaging Intelligence with Proton Magnetic Resonance Spectroscopy
Jung, Rex E.; Gasparovic, Charles; Chavez, Robert S.; Caprihan, Arvind; Barrow, Ranee; Yeo, Ronald A.
Intelligence, v37 n2 p192-198 Mar-Apr 2009
Proton magnetic resonance spectroscopy ([to the first power]H-MRS) is a technique for the assay of brain neurochemistry "in vivo." N-acetylaspartate (NAA), the most prominent metabolite visible within the [to the first power]H-MRS spectrum, is found primarily within neurons. The current study was designed to further elucidate NAA-cognition relationships, particularly whether such relationships are moderated by sex, or tissue type (gray or white matter). We administered standard measures of intelligence to 63 young, healthy subjects and obtained spectroscopic imaging data within a slab of tissue superior to the lateral ventricles. We found that "lower" NAA within right anterior gray matter predicted better performance VIQ (F = 6.83, p = 0.011, r[superscript 2] = 0.10), while "higher" NAA within the right posterior gray matter region predicted better PIQ (F = 8.175, p = 0.006, r[superscript 2] = 0.12). These findings add to the small but growing body of literature linking brain biochemistry to intelligence in normal healthy subjects using [to the first power]H-MRSI. (Contains 2 figures and 2 tables.)
Elsevier. 6277 Sea Harbor Drive, Orlando, FL 32887-4800. Tel: 877-839-7126; Tel: 407-345-4020; Fax: 407-363-1354; e-mail: usjcs@elsevier.com; Web site: http://www.elsevier.com
Publication Type: Journal Articles; Reports - Research
Education Level: N/A
Audience: N/A
Language: English
Sponsor: N/A
Authoring Institution: N/A