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ERIC Number: EJ829454
Record Type: Journal
Publication Date: 2007
Pages: 6
Abstractor: As Provided
Reference Count: 11
ISSN: ISSN-0009-2479
A Case Study of Representing Signal Transduction in Liver Cells as a Feedback Control Problem
Singh, Abhay; Jayaraman, Arul; Hahn, Juergen
Chemical Engineering Education, v41 n3 p177-182 Sum 2007
Cell signaling pathways often contain feedback loops where proteins are produced that regulate signaling. While feedback regulatory mechanisms are commonly found in signaling pathways, there is no example available in the literature that is simple enough to be presented in an undergraduate control class. This paper presents a simulation study of cell signaling in liver cells where it is shown that the cellular regulatory response can be represented by linear transfer functions for certain levels of stimulation. (Contains 9 figures.)
Chemical Engineering Education, Chemical Engineering Division of ASEE. P.O. Box 142097, Gainesville FL 32614. Tel: 352-392-0861; Fax: 352-392-0861; e-mail:; Website:
Publication Type: Journal Articles; Reports - Research
Education Level: Higher Education
Audience: N/A
Language: English
Sponsor: N/A
Authoring Institution: N/A