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ERIC Number: EJ828655
Record Type: Journal
Publication Date: 2009
Pages: 5
Abstractor: As Provided
Reference Count: 0
ISSN: ISSN-0891-4222
Nitric Oxide and Interlukin-6 Levels in Intellectual Disability Adults with Epilepsy
Carmeli, Eli; Beiker, Reut; Morad, Mohammed
Research in Developmental Disabilities: A Multidisciplinary Journal, v30 n3 p567-571 May-Jun 2009
Nitric oxide (NO) and interlukin-6 (IL-6) are highly reactive mediators that have been shown to play different roles in a variety of different biological process. The role of NO and IL-6 in the neuropathogenesis of brain seizures is still questionable. In order to evaluate the role of NO and IL-6 in neurological disorders such as seizures, we investigated 19 adults with intellectual disability (ID) who suffer from epilepsy and treated for convulsions. NO metabolites (NOx) and IL-6 levels in serum obtained after night-sleep were significantly high among ID individuals diagnosed with epilepsy versus ID people without epilepsy. These results indicated that NOx and IL-6 may have a pathophysiological role in convulsions. Consequently, we suggest that professionals consider chemical inhibitors that might be helpful against the function of NO and IL-6. (Contains 1 figure and 1 table.)
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Publication Type: Journal Articles; Reports - Research
Education Level: N/A
Audience: N/A
Language: English
Sponsor: N/A
Authoring Institution: N/A