NotesFAQContact Us
Search Tips
Peer reviewed Peer reviewed
Direct linkDirect link
ERIC Number: EJ827440
Record Type: Journal
Publication Date: 2008-Jul
Pages: 3
Abstractor: As Provided
Reference Count: 15
ISSN: ISSN-0021-9584
Evaluating Mechanisms of Dihydroxylation by Thin-Layer Chromatography: A Microscale Experiment for Organic Chemistry
Burlingham, Benjamin T.; Rettig, Joseph C.
Journal of Chemical Education, v85 n7 p959-961 Jul 2008
A microscale experiment is presented in which cyclohexene is dihydroxylated under three sets of conditions: epoxidation-hydrolysis, permanganate oxidation, and the Woodward dihydroxylation. The products of the reactions are determined by the use of thin-layer chromatography. Teams of students are presented with proposed mechanisms for each dihydroxylation and are asked to evaluate them in light of data collected during the experiment. Both the timing of the lab in relation to the classroom curriculum and alternative applications of the lab are discussed. (Contains 1 figure and 2 notes.)
Division of Chemical Education of the American Chemical Society. Subscription Department, P.O. Box 1267, Bellmawr, NJ 08099-1267. Tel: 800-691-9846; Tel: 856-931-5825; Fax: 856-931-4115; e-mail:; Web site:
Publication Type: Journal Articles; Reports - Evaluative
Education Level: Higher Education
Audience: N/A
Language: English
Sponsor: N/A
Authoring Institution: N/A