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ERIC Number: EJ820899
Record Type: Journal
Publication Date: 2007-Dec
Pages: 3
Abstractor: As Provided
Reference Count: 9
ISBN: N/A
ISSN: ISSN-0021-9584
Illustrating the Concepts of Isotopes and Mass Spectrometry in Introductory Courses: A MALDI-TOF Mass Spectrometry Laboratory Experiment
Dopke, Nancy Carter; Lovett, Timothy Neal
Journal of Chemical Education, v84 n12 p1968-1970 Dec 2007
Mass spectrometry is a widely used and versatile tool for scientists in many different fields. Soft ionization techniques such as matrix-assisted laser desorption/ionization (MALDI) allow for the analysis of biomolecules, polymers, and clusters. This article describes a MALDI mass spectrometry experiment designed for students in introductory courses that provides hands-on experience with research instrumentation and reinforces the course concepts of isotopes, molecular masses, and molecular formulas. The students prepare peptide samples for mass analysis and then collect and analyze mass spectral data. This experiment could easily be adapted to an instructor's available or preferred soft ionization technique. (Contains 1 figure.)
Division of Chemical Education of the American Chemical Society. Subscription Department, P.O. Box 1267, Bellmawr, NJ 08099-1267. Tel: 800-691-9846; Tel: 856-931-5825; Fax: 856-931-4115; e-mail: jchemed@egpp.com; Web site: http://www.jce.divched.org
Publication Type: Journal Articles; Reports - Descriptive
Education Level: Higher Education
Audience: Students; Teachers
Language: English
Sponsor: N/A
Authoring Institution: N/A