NotesFAQContact Us
Search Tips
Peer reviewed Peer reviewed
Direct linkDirect link
ERIC Number: EJ820860
Record Type: Journal
Publication Date: 2007-Nov
Pages: 4
Abstractor: As Provided
Reference Count: 27
ISSN: ISSN-0021-9584
Synthesis of Triarylmethane and Xanthene Dyes Using Electrophilic Aromatic Substitution Reactions
McCullagh, James V.; Daggett, Kelly A.
Journal of Chemical Education, v84 n11 p1799-1802 Nov 2007
The synthesis of dyes has long been a popular topic in organic chemistry laboratory experiments because it allows students to see first hand that reactions learned in class can be used to make compounds with useful applications. In this experiment electrophilic aromatic substitution reactions are used to synthesize several triarylmethane and xanthene dyes (fluorescein, erythrosin B, thymolphthalein, and rhodamine B). These dyes can be readily synthesized using equipment found in most common second-year organic labs. Hydroscopic Lewis acids, which are often troublesome to use in a typical lab setup, are avoided. The dyes synthesized in this experiment can each be completed in one four-hour laboratory session. Approximately 30 minutes in a subsequent period will be required for UV-vis analysis, and the student samples give UV-vis spectra that match commercially available dye samples. (Contains 4 figures/schemes, 1 table and 1 note.)
Division of Chemical Education of the American Chemical Society. Subscription Department, P.O. Box 1267, Bellmawr, NJ 08099-1267. Tel: 800-691-9846; Tel: 856-931-5825; Fax: 856-931-4115; e-mail:; Web site:
Publication Type: Journal Articles; Reports - Research
Education Level: Higher Education
Audience: N/A
Language: English
Sponsor: N/A
Authoring Institution: N/A