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ERIC Number: EJ820850
Record Type: Journal
Publication Date: 2007-Oct
Pages: 3
Abstractor: As Provided
Reference Count: 9
ISSN: ISSN-0021-9584
Discovering Electronic Effects of Substituents in Nitrations of Benzene Derivatives Using GC-MS Analysis
Clennan, Malgorzata M.; Clennan, Edward L.
Journal of Chemical Education, v84 n10 p1679-1681 Oct 2007
The nitration of six benzene derivatives having a range of substituents that differ in electronic effects were followed by GC-MS analyses of the crude reaction mixtures and adapted for the second-year organic laboratory. Students pool their results and identify the products by analyzing the mass spectral data of the isomers and by comparing them to the GC-MS analysis of authentic samples. Students determine which substituents predominantly direct nitration to the ortho- or para- and to the meta positions. This simple discovery-oriented experiment illustrates and reinforces the lecture material and provides students with first-hand knowledge of how textbook conclusions are determined in a laboratory situation. (Contains 1 figure, 1 table and 4 notes.)
Division of Chemical Education of the American Chemical Society. Subscription Department, P.O. Box 1267, Bellmawr, NJ 08099-1267. Tel: 800-691-9846; Tel: 856-931-5825; Fax: 856-931-4115; e-mail:; Web site:
Publication Type: Journal Articles; Reports - Evaluative
Education Level: Higher Education; Postsecondary Education
Audience: N/A
Language: English
Sponsor: N/A
Authoring Institution: N/A