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ERIC Number: EJ820738
Record Type: Journal
Publication Date: 2007-Mar
Pages: 3
Abstractor: As Provided
Reference Count: 5
ISSN: ISSN-0021-9584
The Roles of Acids and Bases in Enzyme Catalysis
Weiss, Hilton M.
Journal of Chemical Education, v84 n3 p440-442 Mar 2007
Many organic reactions are catalyzed by strong acids or bases that protonate or deprotonate neutral reactants leading to reactive cations or anions that proceed to products. In enzyme reactions, only weak acids and bases are available to hydrogen bond to reactants and to transfer protons in response to developing charges. Understanding this difference goes a long way toward applying organic concepts to the mechanisms of bioorganic chemistry. (Contains 1 note and 2 schemes/figures.)
Division of Chemical Education of the American Chemical Society. Subscription Department, P.O. Box 1267, Bellmawr, NJ 08099-1267. Tel: 800-691-9846; Tel: 856-931-5825; Fax: 856-931-4115; e-mail:; Web site:
Publication Type: Journal Articles; Reports - Descriptive
Education Level: Higher Education; Postsecondary Education
Audience: N/A
Language: English
Sponsor: N/A
Authoring Institution: N/A