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ERIC Number: EJ816715
Record Type: Journal
Publication Date: 2008-Oct
Pages: 4
Abstractor: As Provided
Reference Count: 0
ISSN: ISSN-1557-1874
Adverse Reaction to Nicotine Gum in Malay Female Smoker: A Case Report
Noorzurani, Md Haris Robson; Bond, Alyson; Wolff, Kim
International Journal of Mental Health and Addiction, v6 n4 p564-567 Oct 2008
Nicotine replacement therapies (NRT) are prescribed in smoking cessation programmes to help smokers stop smoking. The ideal dosage of NRT should control cravings and withdrawal symptoms but avoid adverse reactions. This report describes a case of adverse reaction to nicotine gum in a female Malay smoker. Assays taken 2 h after the gum, showed that her plasma cotinine/nicotine ratio was 0.4, indicating poor nicotine metabolic status. She developed nausea, severe vomiting and diarrhoea with raised blood pressure and pulse rate, following the administration of a piece of 2 mg nicotine gum on an empty stomach. This was observed in the course of a study to determine nicotine metabolism. Nicotine gum may be associated with adverse reactions in those with poor nicotine metabolic rate. Further investigation is required into the clinical effects of nicotine gum in those with poor nicotine metabolic status.
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Publication Type: Journal Articles; Reports - Research
Education Level: N/A
Audience: N/A
Language: English
Sponsor: N/A
Authoring Institution: N/A