ERIC Number: EJ812899
Record Type: Journal
Publication Date: 2008-May
Abstractor: As Provided
Reference Count: 0
Meta-Analysis of Randomized, Controlled Treatment Trials for Pediatric Obsessive-Compulsive Disorder
Watson, Hunna J.; Rees, Clare S.
Journal of Child Psychology and Psychiatry, v49 n5 p489-498 May 2008
Objective: To conduct a meta-analysis on randomized, controlled treatment trials of pediatric obsessive-compulsive disorder (OCD). Method: Studies were included if they employed randomized, controlled methodology and treated young people (19 years or under) with OCD. A comprehensive literature search identified 13 RCTs containing 10 pharmacotherapy to control comparisons (N = 1016) and five cognitive-behavioral therapy (CBT) to control comparisons (N = 161). Results: Random effects modeling yielded statistically significant pooled effect size (ES) estimates for pharmacotherapy (ES = 0.48, 95% CI = 0.36 to 0.61, p less than 0.00001) and CBT (ES = 1.45, 95% CI = 0.68 to 2.22, p = 0.002). The results were robust to publication bias. Conclusions: This is the first meta-analysis of treatment RCTs for pediatric OCD. CBT and pharmacotherapy were the only treatments effective beyond control in alleviating OCD symptoms. CBT showed a greater ES than pharmacotherapy. Previous meta-analyses that included uncontrolled trials exaggerated the efficacy of both treatments.
Descriptors: Pediatrics, Meta Analysis, Antisocial Behavior, Child Behavior, Behavior Disorders, Literature Reviews, Drug Therapy, Comparative Analysis, Behavior Modification, Cognitive Restructuring, Counseling Techniques, Counseling Effectiveness, Outcomes of Treatment, Effect Size
Blackwell Publishing. 350 Main Street, Malden, MA 02148. Tel: 800-835-6770; Tel: 781-388-8599; Fax: 781-388-8232; e-mail: email@example.com; Web site: http://www.blackwellpublishing.com/jnl_default.asp
Publication Type: Journal Articles; Reports - Research
Education Level: N/A
Authoring Institution: N/A