ERIC Number: EJ804217
Record Type: Journal
Publication Date: 2008-Aug
Abstractor: As Provided
Reference Count: 0
Oppositional Defiant Disorder as a Clinical Phenotype in Children with Autism Spectrum Disorder
Gadow, Kenneth D.; DeVincent, Carla J.; Drabick, Deborah A. G.
Journal of Autism and Developmental Disorders, v38 n7 p1302-1310 Aug 2008
To examine the validity of oppositional defiant disorder (ODD) as a clinical phenotype distinct from attention-deficit hyperactivity disorder (ADHD), parents and teachers completed a DSM-IV-referenced rating scale and a background questionnaire for 608 children (ages 3-12 years) with autism spectrum disorder (ASD). The ASD sample was separated into four groups: ODD, ADHD, ODD + ADHD, and neither (NONE). Comparison samples were non-ASD clinic (n = 326) and community (n greater than 800) controls. In the ASD sample, all three ODD/ADHD groups were clearly differentiated from the NONE group, and the ODD + ADHD group had the most severe co-occurring symptoms, medication use, and environmental disadvantage. There were few differences between ASD + ODD and ASD + ADHD groups. Findings for ASD and control samples were similar, supporting overlapping mechanisms in the pathogenesis of ODD.
Descriptors: Autism, Hyperactivity, Attention Deficit Disorders, Behavior Disorders, Children, Validity, Differences, Pervasive Developmental Disorders
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Publication Type: Journal Articles; Reports - Evaluative
Education Level: N/A
Authoring Institution: N/A