Systematic Treatment Selection (STS) is a form of technical eclectism that develops and plans treatments using empirically founded principles of psychotherapy. It is a model that provides systematic guidelines for the utilization of different psychotherapeutic strategies based on patient qualities and problem characteristics. Historically, it stems from accumulating evidence that no single theory is effective in treating all patients and common characteristics shared among different theoretical philosophies. A review of the literature and further research resulted in the extraction of four main decisional domains that are involved in determining effective treatment strategies. These domains include: (1) patient predisposing qualities, (2) treatment context, (3) relationship variables, and (4) intervention selection. These main principles provide the basis for which guidelines have been developed to systematically individualize treatment plans. The next step in the process is to effectively disseminate and implement this model, in which students and clinicians are taught to operate from a patient based rather than a theory based perspective.