ERIC Number: EJ797504
Record Type: Journal
Publication Date: 2008-Jul
Reference Count: N/A
Level of Functioning in Autism Spectrum Disorders: Phenotypic Congruence among Affected Siblings
Goin-Kochel, Robin P.; Mazefsky, Carla A.; Riley, Brien P.
Journal of Autism and Developmental Disorders, v38 n6 p1019-1027 Jul 2008
Little evidence supports that siblings with autism exhibit the same behaviors; however, some findings suggest that level of functioning shows familial aggregation. We tested this notion among multiplex families participating with the Autism Genetic Resource Exchange (AGRE) Consortium, using scores on the "Peabody Picture Vocabulary Test-Third Edition" (N = 204 families), the "Ravens Colored Progressive Matrices" (N = 226 families), and the "Vineland Adaptive Behavior Scales" (N = 348 families). Intraclass Correlation Coefficients revealed that siblings with autism/autism spectrum disorders (ASD) were more similar on measures of verbal and nonverbal IQ and adaptive functioning than were unrelated children with autism/ASD. Preliminary twin correlations indicated strong genetic effects for some skill domains and the influence of shared environmental factors for others.
Descriptors: Siblings, Autism, Adjustment (to Environment), Genetics, Correlation, Pervasive Developmental Disorders, Behavior Problems, Verbal Communication, Nonverbal Communication, Intelligence Quotient, Environmental Influences
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Publication Type: Journal Articles; Reports - Research
Education Level: N/A
Authoring Institution: N/A
Identifiers - Assessments and Surveys: Peabody Picture Vocabulary Test; Raven Progressive Matrices; Vineland Adaptive Behavior Scales