ERIC Number: EJ797503
Record Type: Journal
Publication Date: 2008-Jul
Abstractor: As Provided
Reference Count: 0
Intestinal Permeability and Glucagon-Like Peptide-2 in Children with Autism: A Controlled Pilot Study
Robertson, Marli A.; Sigalet, David L.; Holst, Jens J.; Meddings, Jon B.; Wood, Julie; Sharkey, Keith A.
Journal of Autism and Developmental Disorders, v38 n6 p1066-1071 Jul 2008
We measured small intestinal permeability using a lactulose:mannitol sugar permeability test in a group of children with autism, with current or previous gastrointestinal complaints. Secondly, we examined whether children with autism had an abnormal glucagon-like peptide-2 (GLP-2) response to feeding. Results were compared with sibling controls and children without developmental disabilities. We enrolled 14 children with autism, 7 developmentally normal siblings of these children and 8 healthy, developmentally normal, unrelated children. Our study did not detect differences in these measures of gastrointestinal function in a group of children with autism.
Descriptors: Siblings, Autism, Developmental Disabilities, Comparative Analysis, Child Health, Human Body
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Publication Type: Journal Articles; Reports - Research
Education Level: N/A
Authoring Institution: N/A