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ERIC Number: EJ797421
Record Type: Journal
Publication Date: 2008-Jul
Pages: 9
Abstractor: Author
Reference Count: 0
ISSN: ISSN-0278-2626
Microstructural Integrity of the Corpus Callosum Linked with Neuropsychological Performance in Adolescents
Fryer, Susanna L.; Frank, Lawrence R.; Spadoni, Andrea D.; Theilmann, Rebecca J.; Nagel, Bonnie J.; Schweinsburg, Alecia D.; Tapert, Susan F.
Brain and Cognition, v67 n2 p225-233 Jul 2008
Background: Diffusion tensor imaging (DTI) has revealed microstructural aspects of adolescent brain development, the cognitive correlates of which remain relatively uncharacterized. Methods: DTI was used to assess white matter microstructure in 18 typically developing adolescents (ages 16-18). Fractional anisotropy (FA) and mean diffusion (MD) were evaluated within the splenium and body of the corpus callosum in relation to cognitive performance. Results: Visuospatial construction abilities were associated with white matter integrity in both the splenium and body of the corpus callosum, while only splenium integrity was associated with language and psychomotor function. Conclusion: Results suggest that, for typically developing adolescents, white matter coherence positively relates to visuospatial, psychomotor, and language skills. These findings may have implications for the cognitive functioning of clinical populations in which typical white matter development is altered. (Contains 2 tables and 2 figures.)
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Publication Type: Journal Articles; Reports - Research
Education Level: N/A
Audience: N/A
Language: English
Sponsor: N/A
Authoring Institution: N/A