ERIC Number: EJ797270
Record Type: Journal
Publication Date: 2008-Jun
Reference Count: 0
Investigating Birth Control: Comparing Oestrogen Levels in Patients Using the Ortho Evra[R] Patch versus the Ortho-Cyclen[R] Pill
Laurent, Theresa A.
Teaching Mathematics and Its Applications: An International Journal of the IMA, v27 n2 p81-90 Jun 2008
Recent drug studies have investigated the incidence of blood clots among patients using the Ortho Evra[R] birth control patch. In this article, the author describes an investigation of oestrogen levels in the body resulting from the application of the Ortho Evra[R] birth control patch versus daily use of Ortho-Cyclen[R] birth control pills. Prescribing information provided by the manufacturer and mathematical models from pharmacokinetics are used to investigate differences between the two birth control methods. Given the pharmacokinetic information on these drugs, applied calculus students are asked to recalculate the size of the patch so that the areas under the curves are equal. Their findings are compared to studies reported in the prescribing information produced by Ortho McNeil Pharmaceuticals, the manufacturers of these products.
Descriptors: Contraception, Mathematical Models, Pharmacology, Calculus, Mathematics Instruction, Teaching Methods, Computation, Patients
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Publication Type: Journal Articles; Reports - Evaluative
Education Level: N/A
Authoring Institution: N/A