ERIC Number: EJ794837
Record Type: Journal
Publication Date: 2008-Jun
Reference Count: 0
Williams Syndrome: A Critical Review of the Cognitive, Behavioral, and Neuroanatomical Phenotype
Martens, Marilee A.; Wilson, Sarah J.; Reutens, David C.
Journal of Child Psychology and Psychiatry, v49 n6 p576-608 Jun 2008
This review critically examines the research findings which characterize the cognitive, behavioral, and neuroanatomical features of Williams syndrome (WS). This article analyzes 178 published studies in the WS literature covering the following areas: 1) General intelligence, 2) Language skills, 3) Visuospatial and face processing skills, 4) Behavior patterns and hypersociability, 5) Musical abilities, and 6) Brain structure and function. We identify methodological issues relating to small sample size, use and type of control groups, and multiple measures of task performance. Previously described "peaks" within the cognitive profile are closely examined to assess their veracity. This review highlights the need for methodologically sound studies that utilize multiple comparison groups, developmental trajectories, and longitudinal analyses to examine the WS phenotype, as well as those that link brain structure and function to the cognitive and behavioral phenotype of WS individuals.
Descriptors: Control Groups, Behavior Patterns, Mental Retardation, Neurology, Brain, Language Skills, Criticism, Genetics, Intelligence, Spatial Ability, Cognitive Processes, Music, Sample Size, Research Methodology, Task Analysis, Profiles, Longitudinal Studies
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Publication Type: Journal Articles; Reports - Evaluative
Education Level: N/A
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