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ERIC Number: EJ792093
Record Type: Journal
Publication Date: 2008
Pages: 13
Abstractor: Author
Reference Count: 28
ISSN: ISSN-0033-2933
Scopolamine Effects Under a Titrating-Delayed-Nonmatching-to-Position Procedure
Porritt, M.; Poling, A.
Psychological Record, v58 n1 p37-49 Win 2008
In a study of working memory, the performance of rats under titrating-delayed-nonmatching- to-position (TDNMTP) procedures was examined. Overall accuracy and the number of trials completed were inversely related to titration value, whereas the highest delay attained was directly related to titration value. When given intraperitoneally, scopolamine significantly reduced the highest delay attained without significantly affecting other performance measures for most administrations. Subcutaneous administrations significantly reduced all performance measures, suggesting that, as in most prior studies, the drug's disruptive effects were not limited to memory processes. These findings demonstrate the feasibility of using TDNMTP procedures with rats, but further research is necessary to determine if such procedures are especially valuable in studying working memory and drug effects thereon. (Contains 4 figures.)
Southern Illinois University Carbondale. Mailcode 4609, Southern Illinois University, Carbondale, IL 62901-4609. Tel: 618-536-7704; e-mail:; Web site:
Publication Type: Journal Articles; Reports - Research
Education Level: N/A
Audience: N/A
Language: English
Sponsor: N/A
Authoring Institution: N/A