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ERIC Number: EJ788525
Record Type: Journal
Publication Date: 2008-Mar
Pages: 7
Abstractor: Author
Reference Count: 15
ISSN: ISSN-1043-4046
Teaching the Physiology of Adaptation to Hypoxic Stress with the Aid of a Classic Paper on High Altitude by Houston and Riley
Tansey, Etain A.
Advances in Physiology Education, v32 n1 p11-17 March 2008
Many pathological conditions exist where tissues exhibit hypoxia or low oxygen tension. Hypoxic hypoxia arises when there is a reduction in the amount of oxygen entering the blood and occurs in healthy people at high altitude. In 1946, research sponsored by the United States Navy led to the collection and subsequent publication of masses of data demonstrating the physiological consequences and adaptations of ascent to high altitude. This article describes how a figure from a 1947 paper from the American Physiological Society Legacy collection (Houston CS, Riley RL. Respiratory and circulatory changes during acclimatization to high altitude. "Am J Physiol" 149: 565-588) may be used to allow students to review their understanding of some of the generalized effects of hypoxia on the body. In particular, this figure summarizes some of the adaptive responses that take place in the oxygen transport system as a consequence of prolonged hypoxia. (Contains 1 figure, 1 table and 1 footnote.)
American Physiological Society. 9650 Rockville Pike, Bethesda, MD 20814-3991. Tel: 301-634-7164; Fax: 301-634-7241; e-mail:; Web site:
Publication Type: Journal Articles; Reports - Descriptive
Education Level: N/A
Audience: N/A
Language: English
Sponsor: N/A
Authoring Institution: N/A