ERIC Number: EJ785836
Record Type: Journal
Publication Date: 2006-Dec
Reference Count: 0
Serotonin Transporter (5-HTTLPR) Genotype, Childhood Abuse, and Suicide Attempts in Adult Psychiatric Inpatients
Gibb, Brandon E.; McGeary, John E.; Beevers, Christopher G.; Miller, Ivan W.
Suicide and Life-Threatening Behavior, v36 n6 p687-693 Dec 2006
There is growing evidence that a functional polymorphism in the serotonin transporter gene (5-HTTLPR) moderates the impact of negative life events (e.g., childhood abuse) on the development of depression. However, it is unclear whether the gene x environment interaction predicts suicide attempts specifically. In addition, previous studies have not examined different forms of childhood abuse separately. In the current study, we found that 5-HTTLPR genotype moderated the link between childhood physical and sexual, but not emotional, abuse and adult psychiatric inpatients' histories of suicide attempts.
Descriptors: Experience, Child Abuse, Suicide, Patients, Depression (Psychology), Psychological Patterns, Adults, Genetics, Environmental Influences, Nature Nurture Controversy, Emotional Response, Psychiatry, Self Destructive Behavior
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Publication Type: Journal Articles; Reports - Research
Education Level: N/A
Authoring Institution: N/A