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ERIC Number: EJ785566
Record Type: Journal
Publication Date: 2008-Feb
Pages: 4
Abstractor: Author
Reference Count: 0
ISBN: N/A
ISSN: ISSN-1072-0502
AX+/BX- Discrimination Learning in the Fear-Potentiated Startle Paradigm in Monkeys
Winslow, James T.; Noble, Pamela L.; Davis, Michael
Learning & Memory, v15 n2 p63-66 Feb 2008
Individuals with anxiety disorders often do not respond to safety signals and hence continue to be afraid and anxious. Consequently, it is important to develop paradigms in animals that can directly study brain systems involved in learning about, and responding to, safety signals. We previously developed a discrimination procedure in rats of the form AX+/BX-, where cues A and X presented together are paired with an aversive stimulus and cues B and X presented together predict the absence of an aversive stimulus. The present experiment adapted this procedure to the fear-potentiated startle paradigm in rhesus monkeys.
Cold Spring Harbor Laboratory Press. 500 Sunnyside Blvd, Woodbury, NY 11797-2924. Tel: 800-843-4388; Tel: 516-367-8800; Fax: 516-422-4097; e-mail: cshpres@cshl.edu; Web site: http://www.learnmem.org/
Publication Type: Journal Articles; Reports - Descriptive
Education Level: N/A
Audience: N/A
Language: English
Sponsor: N/A
Authoring Institution: N/A