ERIC Number: EJ782216
Record Type: Journal
Publication Date: 2008-Jan
Reference Count: 0
Compulsive, Self-Injurious, and Autistic Behavior in Children and Adolescents with Fragile X Syndrome
Hall, Scott S.; Lightbody, Amy A.; Reiss, Allan L.
American Journal on Mental Retardation, v113 n1 p44-53 Jan 2008
Compulsive, self-injurious, and autistic behaviors were examined in 31 boys and 29 girls with fragile X syndrome aged 5 to 20 years. Self-injurious behavior occurred in 58% of boys and 17% of girls, whereas compulsive behavior occurred in 72% of boys and 55% of girls and did not appear to be associated with self-injurious behavior. Fifty percent of boys and 20% of girls met diagnostic criteria for autism on the ADOS-G. Girls who showed compulsive behavior had lower levels of FMRP than girls who did not show compulsive behavior, and boys with autistic symptoms had lowered levels of cortisol. Taken together, these data suggest that autistic and compulsive behaviors are highly prevalent in fragile X syndrome and that lowered levels of FMRP and cortisol may be biological markers for these behaviors.
Descriptors: Self Destructive Behavior, Autism, Mental Retardation, Children, Adolescents, Psychological Patterns, Clinical Diagnosis, Evaluation Criteria, Symptoms (Individual Disorders), Biochemistry
American Association on Intellectual and Developmental Disabilities. P.O. Box 1897, Lawrence, KS 66044-1897. Tel: 785-843-1235; Fax: 785-843-1274; e-mail: AJMR@allenpress.com; Web site: http://aaidd.allenpress.com
Publication Type: Journal Articles; Reports - Research
Education Level: N/A
Authoring Institution: N/A