Several studies have demonstrated relationships between loneliness and numerous psychological and physical difficulties among college students. The purpose of this study was to examine whether loneliness might be a factor associated with increased risk of self-injury among college students. The findings did not support the hypothesis that self-injury would be associated with elevated levels of loneliness. The findings were significant but in the opposite direction than expected. Furthermore, the findings regarding gender are in contrast to findings of previous research. (Contains 2 tables.)