ERIC Number: EJ776899
Record Type: Journal
Publication Date: 2007-Oct
Reference Count: 0
Empirically Derived Subtypes of Adolescent Depression: Latent Profile Analysis of Co-Occurring Symptoms in the Treatment for Adolescents with Depression Study (TADS)
Herman, Keith C.; Ostrander, Rick; Walkup, John T.; Silva, Susan G.; March, John S.
Journal of Consulting and Clinical Psychology, v75 n5 p716-728 Oct 2007
A latent profile analysis was conducted on the co-occurring symptoms of 423 adolescents diagnosed with major depressive disorder as part of the Treatment for Adolescents with Depression Study (TADS), a multisite, randomized treatment trial. The participants had a mean (SD) age of 14.6 (1.5) years; of the sample, 45.6% was male and 73.8% was white. Scores on the primary subscales of Conners' Parent Rating Scale-Revised were used as indicators in the analysis. Five classes of symptoms best described the clinical presentation of adolescents enrolled in the TADS. Of the adolescents in the sample, 80% were assigned to classes with clinically significant elevations on 1 or more subscales of the Children's Depression Rating Scale-Revised. The 5 classes met empirical criteria for distinctiveness and were validated against clinical diagnoses, child-rated symptoms, and clinician-rated functional impairment. The findings are consistent with prior studies that showed a high rate of co-occurring symptoms among depressed adolescents. The discussion focuses on understanding subtypes and comorbidity in adolescent depression as well as the implications for treatment and for prevention.
Descriptors: Adolescents, Depression (Psychology), Symptoms (Individual Disorders), Scores, Measures (Individuals), Rating Scales, Therapy, Prevention, Profiles, Clinical Diagnosis, Evaluation Criteria
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Publication Type: Journal Articles; Reports - Research
Education Level: N/A
Authoring Institution: N/A