Suspension and expulsion are widely used to exclude students with and without disabilities who present problem behaviors in school, despite contentious legal debate and evidence associating these methods with high ecological stress and problematic developmental outcomes. Using selected participant data (N = 1,824) from the SEELS study, the study authors entered multilevel predictors into logistic regression analyses to identify factors associated with higher likelihood of exclusion (HLE) among students in three high-exclusion disability groups: emotional/behavioral disorders (EBD), other health impairment (OHI) with a diagnosis of attention-deficit/hyperactivity disorder (ADHD), and learning disability (LD). When the authors examined disability groups together, HLE was more likely among students with EBD and ADHD compared to students with LD. HLE was also associated with African American ethnicity, older age, male gender, low socioeconomic status, multiple school changes, urban schooling, and having parents who expressed low school satisfaction. However, when the authors examined the disability groups individually, predictor profiles varied markedly by disability type. The authors discuss implications for school programs.