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ERIC Number: EJ763037
Record Type: Journal
Publication Date: 2007-Mar
Pages: 8
Abstractor: Author
Reference Count: 60
ISBN: N/A
ISSN: ISSN-0890-8567
Birth Weight and Attention-Deficit/Hyperactivity Symptoms in Childhood and Early Adolescence: A Prospective Swedish Twin Study
Hultman, Christina M.; Torrang, Anna; Tuvblad, Catherine; Cnattingius, Sven; Larsson, Jan-Olov; Lichtenstein, Paul
Journal of the American Academy of Child & Adolescent Psychiatry, v46 n3 p370 Mar 2007
Objective: To determine whether low birth weight increases the risk of attention-deficit/hyperactivity disorder (ADHD) in childhood and early adolescence. Method: In a population-based sample of 1,480 twin pairs born in the period 1985-1986 ascertained from the Swedish Twin Registry, birth weight was collected prospectively through the Medical Birth Registry. ADHD symptoms were measured with a 14-item checklist covering DSM-III-R criteria (parental rating) at age 8 to 9 years and 13 to 14 years. We used both a dichotomous approach for birth weight (greater than 400 g or 15% weight difference) and ADHD (eight or more symptoms) and continuous measures to investigate between- and within-twin pair effects. Results: Our results showed that low birth weight was a risk factor for symptoms of ADHD and the associations did not diminish when we controlled for genetic influence. The lighter twin in birth weight--discordant pairs had on average 13% higher ADHD symptom score at age 8 to 9 years (p = 0.006) and 12% higher ADHD score at age 13 to 14 years (p = 0.018) compared with the heavier twin. The genetic correlations suggest modest or no genetic overlap between birth weight and ADHD. Conclusions: The hypothesis that low birth weight is associated with the development of ADHD symptoms was supported in this prospective twin study. Fetal growth restriction seems to represent a modest but fairly consistent environmental influence on the development of ADHD symptoms. (Contains 3 tables an 1 figure.)
Lippincott Williams & Wilkins. P.O. Box 1600, Hagerstown, MD 21741. Tel: 800-638-3030; Tel: 301-223-2300; Fax: 301-223-2400; Web site: http://www.lww.com/product/?0890-8567
Publication Type: Journal Articles; Reports - Research
Education Level: N/A
Audience: N/A
Language: English
Sponsor: N/A
Authoring Institution: N/A
Identifiers - Location: Sweden