ERIC Number: EJ758398
Record Type: Journal
Publication Date: 2006-Nov
Reference Count: N/A
Etiologies of Autism in a Case-Series from Tanzania
Mankoski, Raymond E.; Collins, Martha; Ndosi, Noah K.; Mgalla, Ella H.; Sarwatt, Veronica V.; Folstein, Susan E.
Journal of Autism and Developmental Disorders, v36 n8 p1039-1051 Nov 2006
Most autism has a genetic cause although post-encephalitis cases are reported. In a case-series (N = 20) from Tanzania, 14 met research criteria for autism. Three (M:F = 1:2) had normal development to age 22, 35, and 42 months, with onset of autism upon recovery from severe malaria, attended by prolonged high fever, convulsions, and in one case prolonged loss of consciousness. In four other cases (M:F = 3:1), the temporal relationship between onset of autism and severe infection was close, but possibly spurious since malaria is common in Tanzania and there were indications of abnormal development in the child or a family member. In seven cases, (M:F = 6:1) autism onset was unrelated to malaria. The excess of non-verbal cases (N = 10) is related to local diagnostic practice.
Descriptors: Foreign Countries, Autism, Etiology, Genetics, Case Studies, Child Development, Correlation, Diseases
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Publication Type: Journal Articles; Reports - Research
Education Level: N/A
Authoring Institution: N/A
Identifiers - Location: Tanzania