As population demographics in the United States continue to shift and issues of educational reform are being considered, the promotion of academic success for all children is an ongoing agenda for educators, citizens, and politicians. To provide high-quality education for students from low socioeconomic households and diverse cultural backgrounds, it is essential to examine specific programs and their components that have been shown to be successful with this population. This article examines such program components and describes a specific collaborative program, Take Stock in Children, which has shown positive results in supporting low-income secondary students to prepare for and enroll in higher education.