ERIC Number: EJ697630
Record Type: Journal
Publication Date: 2005-Apr
Reference Count: N/A
Early Huntington's Disease Affects Movements in Transformed Sensorimotor Mappings
Boulet, C.; Lemay, M.; Bedard, M.A.; Chouinard, M.J.; Chouinard, S.; Richer, F.
Brain and Cognition, v57 n3 p236-243 Apr 2005
This study examined the effect of transformed visual feedback on movement control in Huntington's disease (HD). Patients in the early stages of HD and controls performed aiming movements towards peripheral targets on a digitizing tablet and emphasizing precision. In a baseline condition, HD patients were slower but showed few precision problems in aiming. When visual feedback was inverted in both vertical and horizontal axes, patients showed problems in initial and terminal phases of movement where feedback is most critical. When visual feedback was inverted along a single axis as in a mirror-inversion, HD patients showed large deviations and over-corrections before adaptation. Adaptation was similar in both groups. These results suggest that HD impairs on-line error correction in novel movements.
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Publication Type: Journal Articles
Education Level: N/A
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Identifiers - Location: New York