ERIC Number: EJ696596
Record Type: Journal
Publication Date: 2004-Oct-1
Reference Count: N/A
Huntington Disease: A Case Study of Early Onset Presenting as Depression
Duesterhus, Pia; Schimmelmann, Benno Graf; Wittkugel, Oliver; Schulte-Markwort, Michael
Journal of the American Academy of Child and Adolescent Psychiatry, v43 n10 p1293-1297 Oct 2004
Huntington disease is a dominantly inherited, neurodegenerative disease characterized by choreiform movement disturbances and dementia, usually with adult onset. The rare juvenile-onset Huntington disease differs from the adult phenotype. A case presenting twice, at age 10 with all the signs of a major depression and age 14 with mutism and rigidity, is reported. Meanwhile, the father developed the adult variant of Huntington disease. The boy's diagnosis was confirmed by molecular genetic analysis and magnetic resonance imaging. It is important to be aware of hereditary conditions such as Huntington disease and to provide family counseling before genetic testing and after the diagnosis is confirmed.
Descriptors: Dementia, Psychiatry, Identification, Diseases, Family Counseling, Depression (Psychology), Radiology, Genetics
Lippincott Williams & Wilkins, P.O. Box 1620, Hagerstown, MD 21741. Tel: 800-638-3030 (Toll Free); Fax: 301-223-2400.
Publication Type: Journal Articles; Reports - Research
Education Level: N/A
Authoring Institution: N/A
Identifiers - Location: New York